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Graupner, Michael

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Current Projects

Computational Models of Addiction



Graupner, M., Maex, R., and Gutkin, B.S., Endogenous cholinergic inputs and local circuit mechanisms govern the phasic mesolimbic dopamine response to nicotine, PLoS Computational Biology, in press, (2013).

Tolu, S., Eddine, R., Marti, F., David, V., Graupner, M., Baudonnat, S.P.M., Besson, M., Reperant, C., Zemdegs, J., Pages, C., Caboche, J., Gutkin, B., Gardier, A.M., Changeux, J., Faure, P., and Maskos, U., Co-activation of VTA DA and GABA neurons mediates nicotine reinforcement, Molecular Psychiatry, in press, (2012).
Graupner, M. and Gutkin, B.S., Modelling Local Circuit Mechanisms for Nicotine Control of Dopamine Activity, in: Computational Neuroscience of Drug Addiction, eds. Gutkin, B.S. and Ahmed, S.H., Computational Neuroscience Series, Springer Verlag, 10, 111-144 (2011).

Graupner, M. and Gutkin, B., Modeling nicotinic neuromodulation from global functional and network levels to nAChR based mechanisms, Acta Pharmacol Sin, 30(6), 681–6 (2009).
Ahmed, S.H., Graupner, M., and Gutkin, B., Computational Approaches to the Neurobiology of Drug Addiction, Pharmacopsychiatry, 42(Suppl. 1), S144-S152 (2009).

Graupner, M. and Brunel, N., STDP in a bistable synapse model based on CaMKII and associated signaling pathways, PLoS Comput Biol, 3(11), e221, 2299-2323 (2007).

Graupner, M., Erler, F., and Meyer-Hermann, M., A theory of Plasma Membrane Calcium Pump stimulation and activity, J Biol Phys, 31(2), 183-206 (2005).